VDJbase now provides AIRR-seq study metadata that follows the MiAIRR schema. For those studies that are listed in the iReceptor gateway, the metadata reflects that served by the gateway. For other studies, the metadata provided by VDJbase has been converted to MiAIRR attributes. This means that there are many more columns to choose from on… Continue reading MiAIRR metadata in VDJbase
The IGH records are now processed with a pipeline that provides improved handling of sequences that are duplicated in the reference set: that is, multiple allele definitions having the same sequence. A bug in OGRDBstats that created incorrect full v-sequence alignments has also been fixed.
The analysis of the Human IGH dataset has now been updated to determine novel sequences based on the actual V length inferred by igblast, enabling greater recognition of variation at the 3′ end. To provide greater detail on the analysis, we now provide the commit id of the pipeline version used for analysis in the… Continue reading IGH Analysis updated
VDJbase now has a dataset based on TRB AIRR-Seq repertoires. This data is analysed in Omer et al., 2022, in which we demonstrate that methods developed for the inference of allelic variants in the B cell repertoire can also be applied to the T cell repertoire. Many T cell studies sequence just a short fraction… Continue reading Human TRB AIRR-Seq datasets added
This summer we added human IGK and IGL AIRR-Seq datasets to VDJbase. These comprise those of the IGH studies which also provided light chain sequencing. You can find details of the studies on the Explore Data page – select the required dataset at the top of the page to view statistics.
VDJbase now includes annotations of two sequences of the Rhesus Macaque IGH locus. The first is from the current rheMac10 Reference Assembly, and the second (which is presented as 13 contigs rather than a single assembly) is from a study by Cirelli et al. Annotation was conducted using Digger. Gene names used follow those from… Continue reading Rhesus Macaque Genomic data added