Tools for working with germline sets

The AIRR-C standard germline sets published in OGRDB use a new naming scheme described in our poster. Because the format of these names may not be compatible with all current pipeline tools, we have released receptor-germline-tools: utilities that can convert to more compatible subgroup-identifier-allele form. If you have issues using the germline sets in your… Continue reading Tools for working with germline sets

Germline Set Creation and Naming

This poster, presented at IMMREP22 (Dresden, July 2022) explains the naming convention used in germline sets on OGRDB, and the underlying approach to germline set creation and maintenance.

New inferred sequences accepted by IMGT

A new batch of inferred receptor sequences, submitted for review through OGRDB, has been accepted by IMGT and should be added to their reference sets shortly. This batch included the first IGK and IGL alleles. We have now affirmed a total of 32 sequences, details of which can be found on the Sequences page.

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IARC Submission Guide Updated

We welcome submissions of previously undocumented alleles of human receptor genes. The Submission Guide explains the process, which involves deposition of sequences and sequence sets in NIH or ENA repositories. Your submission will be reviewed by AIRR‘s Inferred Allele Review Committee, and, if there is sufficient evidence, the sequence will be published on this site… Continue reading IARC Submission Guide Updated

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Allele Review Extended

OGRDB is now accepting V- and J- sequence inferences from the human BCR light and heavy chain. Analysis scripts and submission pages have been updated accordingly.

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