If you have identified previously undocumented alleles in AIRR-Seq repertoires, we invite you to submit them to OGRDB for review and possible inclusion in published germline reference sets.
At present, you can submit human IG or TR V-sequences for consideration. We hope to extend this to cover more species and loci soon.
Qualification criteria
To be considered, submissions must meet the following criteria:
- The repertoire sequences from which inferences are made must be deposited in a long-term archive, and the repertoires must be described in a publication in a peer-reviewed journal.
- Amplification primers must capture the complete V(D)J coding region and must not bind within the V-region.
- Inferences of the novel alleles must be made with a tool that is publicly available, validated and described in a peer-reviewed journal.
Further information can be found in Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming.
Submission process
Please feel free to contact us at any point before or during submission for advice or help. We welcome your submission and will work with you to ensure its success.
Before submission, please process the annotated repertoire(s) with OGRDBstats: this will produce a csv file and a pdf file for each repertoire. You will need these files during submission. Then follow the steps outlined here to create the submission in OGRDB.